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Slide 1: LIVER CIRRHOSIS
- A chronic liver disease
- Leads to scarring and liver dysfunction
- Often irreversible without a transplant
Slide 2: DEFINITION
- Chronic liver condition
Long-term disease damaging liver tissue - Irreversible scarring
Fibrosis replaces healthy liver cells - Disrupts liver function
Affects metabolism, detoxification, digestion
Slide 3: CAUSES
- Chronic alcohol abuse
Most common cause in many regions - Hepatitis B & C
Viral infections causing long-term liver damage - Fatty liver disease
Linked to obesity and diabetes - Autoimmune hepatitis
Body’s immune system attacks liver cells - Genetic disorders
E.g., Hemochromatosis, Wilson’s disease
Slide 4: SIGNS & SYMPTOMS
- Fatigue
Due to poor liver function and anemia - Jaundice
Yellowing skin from excess bilirubin - Abdominal swelling
Ascites from fluid accumulation - Loss of appetite
Often due to nausea or discomfort - Bruising easily
Liver makes fewer clotting factors
Slide 5: COMPLICATIONS
- Portal hypertension
Increased pressure in liver blood vessels - Esophageal varices
Swollen veins that can bleed severely - Hepatic encephalopathy
Toxins affecting brain function - Liver cancer
Cirrhosis raises hepatocellular carcinoma risk - Kidney failure
Known as hepatorenal syndrome
Slide 6: DIAGNOSIS
- Blood tests
Check liver enzymes, bilirubin, clotting - Imaging (Ultrasound, CT, MRI)
Show liver size, nodules, blood flow - Liver biopsy
Confirms fibrosis or cirrhosis - Endoscopy
Looks for varices in esophagus/stomach
Slide 7: MANAGEMENT
- Avoid alcohol
Key step to slow disease progression - Treat underlying cause
E.g., antivirals for hepatitis, weight loss - Medications
Reduce complications like ascites, encephalopathy - Liver transplant
Last option when liver fails completely - Regular monitoring
Check liver function and cancer screening
Slide 8: PREVENTION
- Vaccination for Hepatitis B
Prevents one of the major causes - Limit alcohol use
Avoids toxin-induced liver damage - Healthy diet and weight
Prevents fatty liver disease - Safe sex and hygiene
Reduce risk of hepatitis viruses - Regular check-ups
Early detection and control
Slide 9: CONCLUSION
- Cirrhosis is serious and progressive
But can be managed with care - Early diagnosis is vital
Delays damage and improves survival - Lifestyle changes and treatment help
Improve quality of life and reduce risk
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